| GOLEADORES CAMPEONATO NACIONAL 2021 | ||
| Goles | Jugador | Equipo |
| 23 | Gonzalo Sosa | Melipilla |
| 23 | Fernando Zampedri | U. Catolica |
| 20 | Joaquin Larrivey | U. Chile |
| 16 | Cristian Palacios | Union Española |
| 14 | Diego Valencia | U. Catolica |
| 13 | Bryan Carrasco | Palestino |
| 12 | Brayan Hurtado | Cobresal |
| 11 | Ivan Morales | Colo Colo |
| 11 | Leandro Benegas | Curico |
| 11 | Nicolas Guerra | Ñublense |
| 10 | Tobias Figueroa | Antofagasta |
| 10 | Lautaro Palacios | Audax Italiano |
| 10 | Sebastian Saez | Union Calera |
| 9 | Luis Jimenez | Palestino |
| 8 | Leonardo Gil | Colo Colo |
| 8 | Marcelo Larrondo | O'Higgins |
| 8 | Carlos Villanueva | Palestino |
| 8 | Octavio Rivero | Union Calera |
| 8 | Patricio Rubio | Union Española |
| 7 | Joaquin Montecinos | Audax Italiano |
| 7 | Marco Bolados | Colo Colo |
| 7 | Cris Martinez | Huachipato |
| 6 | Byron Nieto | Antofagasta |
| 6 | Eduard Bello | Antofagasta |
| 6 | Matias Donoso | Cobresal |
| 6 | Cecilio Waterman | Everton |
| 6 | Leonardo Valencia | La Serena |
| 6 | Sebastian Leyton | La Serena |
| 6 | Matias Moya | Ñublense |
| 6 | Maximiliano Quinteros | Ñublense |
| 6 | Nicolas Vargas | Ñublense |
| 6 | Facundo Castro | O'Higgins |
| 6 | Marcelino Nuñez | U. Catolica |
| 5 | Fabian Torres | Audax Italiano |
| 5 | Sebastian Varas | Cobresal |
| 5 | Gabriel Costa | Colo Colo |
| 5 | Cristian Zavala | Melipilla |
| 5 | Andres Vilches | Union Calera |
| 4 | Ariel Uribe | Antofagasta |
| 4 | Gonzalo Alvarez | Audax Italiano |
| 4 | Michael Fuentes | Audax Italiano |
| 4 | Felipe Reynero | Cobresal |
| 4 | Javier Parraguez | Colo Colo |
| 4 | Pablo Solari | Colo Colo |
| 4 | Adrian Sanchez | Curico |
| 4 | Felipe Fritz | Curico |
| 4 | Juan Cuevas | Everton |
| 4 | Sebastian Pereira | Everton |
| 4 | Brayan Palmezano | Huachipato |
| 4 | Luciano Nequecaur | Huachipato |
| 4 | Jimmy Martinez | La Serena |
| 4 | Jorge Benitez | La Serena |
| 4 | Juan Ignacio Cavallaro | La Serena |
| 4 | Richard Paredes | La Serena |
| 4 | Federico Mateos | Ñublense |
| 4 | Matias Cahais | O'Higgins |
| 4 | Juan Sanchez Sotelo | Palestino |
| 4 | Misael Davila | Palestino |
| 4 | Jeisson Vargas | Union Calera |
| 4 | Ignacio Lemmo | Union Española |
| 3 | Rodrigo Holgado | Audax Italiano |
| 3 | Mario Pardo | Cobresal |
| 3 | Oscar Salinas | Cobresal |
| 3 | Bayron Oyarzo | Curico |
| 3 | Pablo Parra | Curico |
| 3 | Yerko Leiva | Curico |
| 3 | Maximiliano Rodriguez | Huachipato |
| 3 | Walter Mazzanti | Huachipato |
| 3 | Humberto Suazo | La Serena |
| 3 | Mathias Vidangossy | Melipilla |
| 3 | Bernardo Cerezo | Ñublense |
| 3 | Mathias Pinto | Ñublense |
| 3 | Roberto Gutierrez | Ñublense |
| 3 | Cristian Suarez | Palestino |
| 3 | Alfonso Parot | U. Catolica |
| 3 | Felipe Gutierrez | U. Catolica |
| 3 | Valber Huerta | U. Catolica |
| 3 | Ramon Arias | U. Chile |
| 3 | Matias Marin | Wanderers |
| 3 | Ronnie Fernandez | Wanderers |
| 2 | Andres Robles | Antofagasta |
| 2 | Nicolas Demartini | Antofagasta |
| 2 | Fernando Cornejo | Audax Italiano |
| 2 | Marcos Sebastian Pol | Cobresal |
| 2 | Ignacio Jara | Colo Colo |
| 2 | Luciano Arriagada | Colo Colo |
| 2 | Maximiliano Falcon | Colo Colo |
| 2 | Juan Carlos Gaete | Colo Colo-Cobresal |
| 2 | Felipe Villagran | Curico |
| 2 | Heber Garcia | Curico |
| 2 | Alvaro Madrid | Everton |
| 2 | Christian Bravo | Everton |
| 2 | Cristian Cañozales | Everton |
| 2 | Cristian Menendez | Everton |
| 2 | Benjamin Gazzolo | Huachipato |
| 2 | Claudio Sepulveda | Huachipato |
| 2 | Claudio Torres | Huachipato |
| 2 | Israel Poblete | Huachipato |
| 2 | Joaquin Gutierrez | Huachipato |
| 2 | Matias Fernandez | La Serena |
| 2 | Maximiliano Guerrero | La Serena |
| 2 | Alejandro Camargo | Melipilla |
| 2 | Gustavo Guerreño | Melipilla |
| 2 | Joe Abrigo | Ñublense |
| 2 | Carlos Muñoz | O'Higgins |
| 2 | Matias Meneses | O'Higgins |
| 2 | Matias Sepulveda | O'Higgins |
| 2 | Ramon Fernandez | O'Higgins |
| 2 | Bruno Barticciotto | Palestino |
| 2 | Cesar Cortes | Palestino |
| 2 | Diego Buonanotte | U. Catolica |
| 2 | Jose Pedro Fuenzalida | U. Catolica |
| 2 | Marcelo Cañete | U. Chile |
| 2 | Mario Sandoval | U. Chile |
| 2 | Nicolas Orellana | Union Calera |
| 2 | Pedro Sanchez | Union Calera |
| 2 | Williams Alarcon | Union Calera |
| 2 | Alejandro Chumacero | Union Española |
| 2 | Bastian Yañez | Union Española |
| 2 | Gerardo Navarrete | Union Española |
| 2 | Ignacio Nuñez | Union Española |
| 2 | Juan Pablo Gomez | Union Española |
| 2 | Thomas Galdames | Union Española |
| 2 | Aldrix Jara | Wanderers |
| 2 | Damian Arce | Wanderers |
| 2 | Jose Manuel Aja | Wanderers |
| 2 | Luis Garcia | Wanderers |
| 1 | Jason Flores | Antofagasta |
| 1 | Lukas Soza | Antofagasta |
| 1 | Paulo Magalhaes | Antofagasta |
| 1 | Salvador Cordero | Antofagasta |
| 1 | Carlos Labrin | Audax Italiano |
| 1 | Fabian Carmona | Audax Italiano |
| 1 | Federico Gonzalez | Audax Italiano |
| 1 | Ivan Ochoa | Audax Italiano |
| 1 | Benjamin Osses | Cobresal |
| 1 | Cristian Maidana | Cobresal |
| 1 | Cristopher Mesias | Cobresal |
| 1 | Francisco Valdes | Cobresal |
| 1 | Emiliano Amor | Colo Colo |
| 1 | Diego Urzua | Curico |
| 1 | Fernando Coniglio | Curico |
| 1 | Gabriel Harding | Curico |
| 1 | Jose Rojas | Curico |
| 1 | Leonel Galeano | Curico |
| 1 | Benjamin Rivera | Everton |
| 1 | Denil Maldonado | Everton |
| 1 | Dylan Zuñiga | Everton |
| 1 | Gary Moya | Everton |
| 1 | Matias Campos Lopez | Everton |
| 1 | Maximiliano Ceratto | Everton |
| 1 | Rodrigo Echeverria | Everton |
| 1 | Cesar Huanca | Huachipato |
| 1 | Gonzalo Montes | Huachipato |
| 1 | Ignacio Tapia | Huachipato |
| 1 | Javier Altamirano | Huachipato |
| 1 | Nicolas Baeza | Huachipato |
| 1 | Cesar Munder | La Serena |
| 1 | Facundo Agüero | La Serena |
| 1 | Romulo | La Serena |
| 1 | Santiago Dittborn | La Serena |
| 1 | Aaron Astudillo | Melipilla |
| 1 | Juan Ignacio Duma | Melipilla |
| 1 | Kevin Rojas | Melipilla |
| 1 | Luis Haquin | Melipilla |
| 1 | Branco Provoste | Ñublense |
| 1 | Fernando Cordero | Ñublense |
| 1 | Jonathan Turra | Ñublense |
| 1 | Luis Valenzuela | Ñublense |
| 1 | Alejandro Marquez | O'Higgins |
| 1 | Gustavo Gotti | O'Higgins |
| 1 | Pedro Pablo Hernandez | O'Higgins |
| 1 | Tomas Alarcon | O'Higgins |
| 1 | Bruno Romo | Palestino |
| 1 | Nicolas Berardo | Palestino |
| 1 | Clemente Montes | U. Catolica |
| 1 | Edson Puch | U. Catolica |
| 1 | German Lanaro | U. Catolica |
| 1 | Juan Cornejo | U. Catolica |
| 1 | Juan Leiva | U. Catolica |
| 1 | Tomas Astaburuaga | U. Catolica |
| 1 | Angelo Henriquez | U. Chile |
| 1 | Camilo Moya | U. Chile |
| 1 | Franco Lobos | U. Chile |
| 1 | Gonzalo Espinoza | U. Chile |
| 1 | Junior Fernandes | U. Chile |
| 1 | Yonathan Andia | U. Chile |
| 1 | Ariel Martinez | Union Calera |
| 1 | Bruno Liuzzi | Union Calera |
| 1 | Christian Vilches | Union Calera |
| 1 | Erick Wiemberg | Union Calera |
| 1 | Esteban Valencia | Union Calera |
| 1 | Gonzalo Castellani | Union Calera |
| 1 | Jorge Valdivia | Union Calera |
| 1 | Simon Ramirez | Union Calera |
| 1 | Bryan Rabello | Union Española |
| 1 | Diego Acevedo | Union Española |
| 1 | Gabriel Norambuena | Union Española |
| 1 | Mario Larenas | Union Española |
| 1 | Ruben Farfan | Union Española |
| 1 | Stefano Magnasco | Union Española |
| 1 | Victor Mendez | Union Española |
| 1 | Daniel Gonzalez | Wanderers |
| 1 | Diego Vallejos | Wanderers |
| 1 | Facundo Kidd | Wanderers |
| 1 | Felipe Alvarado | Wanderers |
| 1 | Gabriel Rojas | Wanderers |
| 1 | Juan Carlos Soto | Wanderers |
| 1 | Marco Medel | Wanderers |
| 1 | Sebastian Ubilla | Wanderers |
| 1 | Victor Espinoza | Wanderers |
| 1 | Willian Gama | Wanderers |
| Autogoles | ||
| 1 | Julio Barroso | Everton |
| 1 | Sebastian Pereira | Everton |
| 1 | Sebastian Leyton | La Serena |
| 1 | Fabricio Fontanini | Ñublense |
| 1 | Felipe Seymour | O'Higgins |
| 1 | Matias Cahais | O'Higgins |
| 1 | Cristian Suarez | Palestino |
| 1 | Ramon Arias | U. Chile |
| 1 | Gonzalo Castellani | Union Calera |
| 1 | Victor Gonzalez | Union Calera |
| 1 | Luis Pavez Contreras | Union Española |